Low-dose chloroquine treatment extends the lifespan of aged rats

Abstract excerpt

Dear Editor, Chloroquine (CQ) has long been used as an anti-malarial agent (Wellems and Plowe, 2001). Recently, CQ has also been applied to treat viral infection and related diseases (Wellems and Plowe, 2001; Huang et al., 2020). However, the safety and efficacy of its applications are still under extensive debate (Solomon and Lee, 2009). Here, we discovered that low-dose CQ has a geroprotective effect on...

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