Article
Dysregulation of the CD163-Haptoglobin Axis in the Airways of COPD Patients.
Cells - 21 Dec 2021
Higham Andrew, Baker James M, Jackson Natalie, Shah Rajesh, Lea Simon, Singh Dave
Abstract excerpt
Pulmonary iron levels are increased in chronic obstructive pulmonary disease (COPD) patients. Iron causes oxidative stress and is a nutrient for pathogenic bacteria. Iron may therefore play an important role in the pathophysiology of COPD. The CD163-haptglobin axis plays a central role in the regulation of iron bioavailability. The aim of this study was to examine dysregulation of the CD163-haptglobin axis in...
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