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Article

Treatment of slow-channel congenital myasthenic syndrome in a Thai family with fluoxetine.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia - 1 Feb 2022

Dejthevaporn Charungthai, Wetchaphanphesat Suppachok, Pulkes Teeratorn, Rattanasiri Sasivimol, Engel Andrew G, Witoonpanich Rawiphan

Abstract excerpt

The slow-channel congenital myasthenic syndrome is an autosomal dominant neuromuscular disorder caused by mutations in different subunits of the acetylcholine receptor. Fluoxetine, a common antidepressant and long-lived open-channel blocker of acetylcholine receptor, has been reported to be beneficial in the slow-channel congenital myasthenic syndrome. Here we report a prospective open label study of fluoxetine...

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Identifiers

PMID: 34999496
DOI: 10.1016/j.jocn.2021.12.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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