Article
Analysis of Ki-67 expression in women with breast cancer: Comparative evaluation of two different methodologies by immunophenotyping.
Pathology, research and practice - 1 Feb 2022
Vieira Daniella Serafin Couto, Wopereis Sandro, Walter Laura Otto, de Oliveira Silva Lisandra, Ribeiro Amanda Abdalla Biasi, Wilkens Renato Salerno, Fernandes Bráulio Leal, Reis Manoela Lira, Golfetto Lisléia, Santos-Silva Maria Cláudia
Abstract excerpt
The Ki-67 antigen is a nuclear protein with proven prognostic value in different neoplasms and recognizes the predictive value in breast cancer (BC). No consensus exists on the ideal cutoff point. In this study, Ki-67 expression was evaluated in samples of BC by flow cytometry (FC) and compared with immunohistochemical (IHC) examination. For this, the BC tissue samples were sectioned, macerated, filtered, and...
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