Article
Tailoring treatment for ductal intraepithelial neoplasia of the breast according to Ki-67 and molecular phenotype.
British journal of cancer - 30 Apr 2013
Lazzeroni M, Guerrieri-Gonzaga A, Botteri E, Leonardi M C, Rotmensz N, Serrano D, Varricchio C, Disalvatore D, Del Castillo A, Bassi F, Pagani G, DeCensi A, Viale G, Bonanni B, Pruneri G
Abstract excerpt
BACKGROUND: The post-surgical management of ductal intraepithelial neoplasia (DIN) of the breast is still a dilemma. Ki-67 labelling index (LI) has been proposed as an independent predictive and prognostic factor in early breast cancer. METHODS: The prognostic and predictive roles of Ki-67 LI were evaluated with a multivariable Cox regression model in a cohort of 1171 consecutive patients operated for DIN in a...
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