Article
Development of an Automatic Measurement Method for CD8 and PD-1 Positive T Cells Using Image Analysis Software.
Anticancer research - 1 Jan 2022
Miyata Haruo, Akiyama Yasuto, Iizuka Akira, Kondou Ryota, Maeda Chie, Kanematsu Akari, Watanabe Kyoko, Ashizawa Tadashi, Nagashima Takeshi, Urakami Kenichi, Ohshima Keiichi, Kawata Takuya, Muramatsu Koji, Shiomi Akio, Terashima Masanori, Sugino Takashi, Notsu Akifumi, Mori Keita, Yamaguchi Ken
Abstract excerpt
BACKGROUND/AIM: With the progress in cancer immunotherapy using immune checkpoint blockade (ICB) therapy, histological observations of tumor-infiltrating lymphocyte (TIL) status are needed to evaluate the antitumor effect of ICB using imaging analysis software. MATERIALS AND METHODS: Formalin-fixed paraffin-embedded sections obtained from colorectal cancer and gastric cancer patients with more than 500 single...
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