Article
Differential gene expression in granulosa cells from polycystic ovary syndrome patients with and without insulin resistance: identification of susceptibility gene sets through network analysis.
The Journal of clinical endocrinology and metabolism - 1 Oct 2012
Kaur Surleen, Archer Kellie J, Devi M Gouri, Kriplani Alka, Strauss Jerome F, Singh Rita
Abstract excerpt
CONTEXT: Polycystic ovary syndrome (PCOS) is a heterogeneous, genetically complex, endocrine disorder of uncertain etiology in women. OBJECTIVE: Our aim was to compare the gene expression profiles in stimulated granulosa cells of PCOS women with and without insulin resistance vs. matched controls. RESEARCH DESIGN AND METHODS: This study included 12 normal ovulatory women (controls), 12 women with PCOS without...
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