Article
TRP channel expression correlates with the epithelial-mesenchymal transition and high-risk endometrial carcinoma.
Cellular and molecular life sciences : CMLS - 22 Dec 2021
Van den Eynde Charlotte, De Clercq Katrien, Van Bree Rieta, Luyten Katrien, Annibali Daniela, Amant Frédéric, Han Sileny, Van Nieuwenhuysen Els, Baert Thaïs, Peeraer Karen, Voets Thomas, Van Gorp Toon, Vriens Joris
Abstract excerpt
Transient receptor potential (TRP) channels excel in cellular sensing as they allow rapid ion influx across the plasma membrane in response to a variety of extracellular cues. Recently, a distinct TRP mRNA expression signature was observed in stromal cells (ESC) and epithelial cells (EEC) of the endometrium, a tissue in which cell phenotypic plasticity is essential for normal functioning. However, it is unknown...
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