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Article

Implication of ARID1A Undercurrents and PDL1, TP53 Overexpression in Advanced Gastric Cancer.

Pathology oncology research : POR - 1 Jan 2021

Qadir Jasiya, Majid Sabhiya, Khan Mosin Saleem, Rashid Fouzia, Wani Mumtaz Din, Bhat Showkat Ahmad

Abstract excerpt

AT-rich interactive domain-containing protein 1A (ARID1A), TP53 and programmed cell death-ligand 1 (PDL1) are involved in several protein interactions that regulate the expression of various cancer-related genes involved in the progression of the cell cycle, cell proliferation, DNA repair, and apoptosis. In addition, gene expression analysis identified some common downstream targets of ARID1A and TP53. It has...

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Identifiers

PMID: 34924820
DOI: 10.3389/pore.2021.1609826
PMCID: PMC8677663

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