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Article

Dysregulation of tRNA-derived small RNAs and their potential roles in lupus nephritis

1 Dec 2021

Abstract excerpt

OBJECTIVE: Lupus nephritis (LN) is a major end-organ complication of systemic lupus erythematosus (SLE), and the molecular mechanism of LN is not completely clear. Accumulating pieces of evidence indicate the potential vital role of tRNA-derived small RNAs (tsRNAs) in human diseases. Current study aimed to investigate the potential roles of tsRNAs in LN. METHODS: We herein employed high-throughput sequencing to...

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PMID: 34923866
DOI: 10.1177/09612033211061482

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