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Article

Reconstruction and analysis of the aberrant lncRNA–miRNA–mRNA network in systemic lupus erythematosus

18 Feb 2020

Abstract excerpt

OBJECTIVE: A new perspective of determining the pathophysiology of systemic lupus erythematosus (SLE) development is required. The current study explores the aberrant expression of long non-coding RNAs (lncRNA), microRNA (miRNA) and mRNA. The study further constructs and analyses the lncRNA-miRNA-mRNA network to elucidate their gene regulation roles in SLE. METHOD: We extracted mRNA, lncRNA and miRNA from the...

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PMID: 32070185
DOI: 10.1177/0961203320908927

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