Article
Treatment with immune checkpoint inhibitors after EGFR-TKIs in EGFR-mutated lung cancer.
Thoracic cancer - 1 Feb 2022
Ito Takashi, Nagashima Hiromi, Akiyama Masachika, Utsumi Yu, Sato Hideomi, Chiba Shinji, Sugai Mayu, Ube Kenji, Mori Yoshiaki, Watanabe Kana, Fukuhara Tatsuro, Maemondo Makoto
Abstract excerpt
BACKGROUND: Epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) have become the gold standard for EGFR-mutated non-small cell lung cancer (NSCLC) treatment. Immune checkpoint inhibitors (ICIs) have been developed for the treatment of several malignancies, including lung cancer. However, it is known that ICIs have poorer efficacy in EGFR-mutated NSCLC. METHODS: We collected data for patients...
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