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Article

BRAF Mutation Is Associated with Hyperplastic Polyp-Associated Gastric Cancer.

International journal of molecular sciences - 25 Nov 2021

Fujiwara-Tani Rina, Okamoto Ayaka, Katsuragawa Hiroyuki, Ohmori Hitoshi, Fujii Kiyomu, Mori Shiori, Kishi Shingo, Sasaki Takamitsu, Nakashima Chie, Kawahara Isao, Hojo Yudai, Nishiguchi Yukiko, Mori Takuya, Mizumoto Takeshi, Nagai Kenta, Luo Yi, Kuniyasu Hiroki

Abstract excerpt

Gastric hyperplastic polyps (GHP) are frequently found to be benign polyps and have been considered to have a low carcinogenic potential. The characteristics of the hyperplastic polyp-associated gastric cancer (HPAGC) remain unclear. Therefore, we analyzed samples from 102 GHP patients and identified 20 low-grade atypical GHPs (19.6%), 7 high-grade atypical GHPs (6.9%), and 5 intramucosal cancer samples (4.9%)....

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PMID: 34884530
DOI: 10.3390/ijms222312724
PMCID: PMC8657452

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