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Article

ENPEP as a potential predictor of immune checkpoint inhibitor efficacy.

Cancer medicine - 1 Feb 2022

Wang Aoyun, Chu Han, Jin Zheng, Gong Zhihua, Jia Qingzhu, Zhu Bo

Abstract excerpt

BACKGROUND: The gene ENPEP encodes glutamyl aminopeptidase, which can cut N-terminal aspartic acid from angiotensin II, and is related to tumorigenesis and immune microenvironment, however, the association between the expression of ENPEP and benefits of immune checkpoint inhibitors (ICIs) has had no investigation. METHODS: We assess the immunotherapeutic predictive performance of ENPEP expression and mutation in...

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Identifiers

PMID: 34862755
DOI: 10.1002/cam4.4475
PMCID: PMC8817092

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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