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Autophagy in α-Synucleinopathies—An Overstrained System

12 Nov 2021

Abstract excerpt

Alpha-synucleinopathies comprise progressive neurodegenerative diseases, including Parkinson's disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA). They all exhibit the same pathological hallmark, which is the formation of α-synuclein positive deposits in neuronal or glial cells. The aggregation of α-synuclein in the cell body of neurons, giving rise to the so-called Lewy bodies...

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PMID: 34831366
DOI: 10.3390/cells10113143

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