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Article

Metals in ALS TDP-43 Pathology.

International journal of molecular sciences - 11 Nov 2021

Koski Lassi, Ronnevi Cecilia, Berntsson Elina, Wärmländer Sebastian K T S, Roos Per M

Abstract excerpt

Amyotrophic lateral sclerosis (ALS), Alzheimer's disease, Parkinson's disease and similar neurodegenerative disorders take their toll on patients, caregivers and society. A common denominator for these disorders is the accumulation of aggregated proteins in nerve cells, yet the triggers for these aggregation processes are currently unknown. In ALS, protein aggregation has been described for the SOD1, C9orf72, FUS...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34830074
DOI: 10.3390/ijms222212193
PMCID: PMC8622279

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