Article
BRAF V600E Mutation in Triple-Negative Breast Cancer: A Case Report and Literature Review.
Oncology research and treatment - 1 Jan 2022
Wang Liye, Lu Qianyi, Jiang Kuikui, Hong Ruoxi, Wang Shusen, Xu Fei
Abstract excerpt
BACKGROUND: The B-Raf proto-oncogene (BRAFV600E) gene mutation has been identified in a variety of malignancies, but no evidence of the efficacy of vemurafenib treatment in BRAFV600E mutant breast cancer (BC) has been reported. CASE PRESENTATION: We reported a 60-year-old woman with confirmed triple-negative BC with BRAFV600E mutation. Progression-free survival (PFS) for first-line chemotherapy was 7 months. The...
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