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Exploring the dual role of circRNA and PI3K/AKT pathway in tumors of the digestive system

11 Oct 2023

Abstract excerpt

The interactions among circRNAs, the PI3K/AKT pathway, and their downstream effectors are intricately linked to their functional roles in tumorigenesis. Furthermore, the circRNAs/PI3K/AKT axis has been significantly implicated in the context of digestive system tumors. This axis is frequently abnormally activated in digestive cancers, including gastric cancer, colorectal cancer, pancreatic cancer, and others....

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PMID: 37832407
DOI: 10.1016/j.biopha.2023.115694

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