Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Toward a pathophysiology inspired treatment of VEXAS syndrome.

Seminars in hematology - 1 Oct 2021

Heiblig Maël, Patel Bhavisha A, Groarke Emma M, Bourbon Estelle, Sujobert Pierre

Abstract excerpt

VEXAS syndrome has an unmet need for therapeutic interventions. Even if few data exist regarding the treatment of this newly described syndrome, different options can be proposed given the unique pathophysiological consequences of the clonal dominance of UBA1 mutated hematopoietic stem cells. To date, allogeneic transplantation is the only curative option, but many questions remain regarding the selection of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hematopoietic Stem Cell Transplantation
Share to Lenalidomide
Share to Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Myelodysplastic Syndromes

Share to Transplantation, Homologous

Source

Identifiers

PMID: 34802546
DOI: 10.1053/j.seminhematol.2021.09.001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Toward a pathophysiology inspired treatment of VEXAS syndrome.PMID 34802546Read ↗

VEXAS syndrome: Clinical, hematologic features and a practical approach to diagnosis and management.Semantic proximity Read ↗

Case report of a patient with VEXAS syndrome.Semantic proximity Read ↗

American College of Rheumatology Guidance Statement for Diagnosis and Management of VEXAS Developed by the International VEXAS Working Group Expert Panel.Semantic proximity Read ↗

Clonal hematopoiesis meets an autoinflammatory disease: the new paradigm of VEXAS syndrome.Semantic proximity Read ↗

VEXAS: A review of current understandings and emerging treatment strategies.Semantic proximity Read ↗

Systemic inflammation with myelodysplastic features: VEXAS syndrome.Semantic proximity Read ↗

VEXAS syndrome in adults: A narrative review of genomic pathogenesis, multisystem phenotypes, diagnostic algorithms, and emerging therapeutic strategies.Semantic proximity Read ↗

VEXAS syndrome, a new kid on the block of auto-inflammatory diseases: A hematologist's point of view.Semantic proximity Read ↗

Looking beyond VEXAS: Coexistence of undifferentiated systemic autoinflammatory disease and myelodysplastic syndrome.Semantic proximity Read ↗

VEXAS: where do we stand 2 years later?Semantic proximity Read ↗

Understanding Myelodysplasia and Inflammation through the Lense of VEXAS Syndrome: A ReviewSemantic proximity Read ↗

Case report: diagnosis of VEXAS syndrome in a patient with therapy-resistant large vessel vasculitis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.