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Article

A Novel Strategy for the Detection of SARS-CoV-2 Variants Based on Multiplex PCR-Mass Spectrometry Minisequencing Technology.

Microbiology spectrum - 22 Dec 2021

Zhao Fei, Lu Jinxing, Lu Bing, Qin Tian, Wang Xuemei, Hou Xuexin, Meng Fanliang, Xu Xiaona, Li Tianyi, Zhou Haijian, Zhang Jianzhong, Kan Biao, Huang Ying, Zhang Zehui, Xiao Di

Abstract excerpt

The objective of this study was to construct a novel strategy for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants using multiplex PCR-mass spectrometry minisequencing technique (mPCR-MS minisequencing). Using the nucleic acid sequence of a SARS-CoV-2 nonvariant and a synthetic SARS-CoV-2 variant-carrying plasmid, a matrix-assisted laser desorption ionization-time of flight...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34787499
DOI: 10.1128/Spectrum.01267-21
PMCID: PMC8597632

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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