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Article

A Novel TFG Mutation in a Korean Family with α-Synucleinopathy and Amyotrophic Lateral Sclerosis.

Movement disorders : official journal of the Movement Disorder Society - 1 Feb 2022

Yoo Dallah, Lee Wonjae, Lee Seung-Jae, Sung Jung-Joon, Jeon Gye Sun, Ban Jae-Jun, Shin Chaewon, Kim Jungho, Kim Hyo Sun, Ahn Tae-Beom

Abstract excerpt

BACKGROUND: Tropomyosin-receptor kinase fused gene (TFG) functions as a regulator of intracellular protein packaging and trafficking at the endoplasmic reticulum exit sites. TFG has recently been proposed as a cause of multisystem proteinopathy. OBJECTIVES: Here, we describe a Korean family presenting with Parkinson's disease or amyotrophic lateral sclerosis caused by a novel variant of TFG (c.1148 G > A,...

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PMID: 34779525
DOI: 10.1002/mds.28857

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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