Immune Microenvironment and Response in Prostate Cancer Using Large Population Cohorts.

doi:10.3389/fimmu.2021.686809

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Article

Immune Microenvironment and Response in Prostate Cancer Using Large Population Cohorts.

Frontiers in immunology - 1 Jan 2021

Ren Xiaohan, Chen Xinglin, Zhang Xu, Jiang Silin, Zhang Tongtong, Li Guangyao, Lu Zhongwen, Zhang Dong, Wang Shangqian, Qin Chao

Abstract excerpt

Immune microenvironment of prostate cancer (PCa) is implicated in disease progression. However, previous studies have not fully explored PCa immune microenvironment. This study used ssGSEA algorithm to explore expression levels of 53 immune terms in a combined PCa cohort (eight cohorts; 1,597 samples). The top 10 immune terms were selected based on the random forest analysis and used for immune-related risk score...

Topics

Biomarkers, Tumor
Computational Biology
Databases, Factual
Disease Management
Disease Susceptibility
Gene Expression Profiling
Germany
Humans
Immunotherapy
Male
Molecular Sequence Annotation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Prognosis

Prostatic Neoplasms

Risk Factors

Treatment Outcome

Tumor Microenvironment

Source

Open in PubMed Open full text

Identifiers

PMID: 34777331
DOI: 10.3389/fimmu.2021.686809
PMCID: PMC8585452

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