Article
Local spread of influenza A (H1N1) viruses without a mutation for the maximum duration of an epidemic season in Japan.
Archives of virology - 1 Jan 2022
Tsuneki-Tokunaga Akeno, Kondo Takanori, Kanai Kyosuke, Itagaki Asao, Tsuchie Hideaki, Okada Takayoshi, Kasagi Masaaki, Tanaka Kiyoshi, Hinay Alfredo Jr A, Kageyama Seiji
Abstract excerpt
Close observation of the local transmission of influenza A(H1N1) viruses enabled an estimate of the length of time the virus was transmitted without a mutation. Of 4,448 isolates from 11 consecutive years, 237 isolates could be categorized into 57 strain groups with identical hemagglutinin genes, which were monitored for the entire duration of an epidemic season. In addition, 35 isolates with identical sequences...
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