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Article

HLA class I restriction as a possible driving force for Chikungunya evolution.

PloS one - 26 Feb 2010

Tong Joo Chuan, Simarmata Diane, Lin Raymond T P, Rénia Laurent, Ng Lisa F P

Abstract excerpt

After two decades of quiescence, epidemic resurgence of Chikungunya fever (CHIKF) was reported in Africa, several islands in the Indian Ocean, South-East Asia and the Pacific causing unprecedented morbidity with some cases of fatality. Early phylogenetic analyses based on partial sequences of Chikungunya virus (CHIKV) have led to speculation that the virus behind recent epidemics may result in greater...

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Identifiers

PMID: 20195467
DOI: 10.1371/journal.pone.0009291
PMCID: PMC2829075

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Source receipt: pubmed, retrieved 7 Sept 2026.

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