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Genetic polymorphisms in the PCNXL2 gene are risk factors for thyroid cancer in the Chinese population.

Future oncology (London, England) - 1 Dec 2021

Hao Runmei, Han Peng, Zhang Ling, Bi Ying, Yan Jinfeng, Li Honghui, Bai Yanxia, Xu Chongwen, Li Baiya, Li Huajing

Abstract excerpt

Background: Thyroid cancer is the most common endocrine malignancy and the fastest growing cancer worldwide. Thyroid cancer has the largest genetic component of all cancers. Previous genome-wide association studies indicated that genetic polymorphism in PCNXL2 is related to thyroid cancer susceptibility in European populations. This study aims to determine the influence of PCNXL2 polymorphisms on thyroid cancer...

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PMID: 34747634
DOI: 10.2217/fon-2021-0748

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