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Article

Cisd2 plays an essential role in corneal epithelial regeneration

28 Oct 2021

Abstract excerpt

Background Age-related changes affecting the ocular surface cause vision loss in the elderly. Cisd2 deficiency drives premature aging in mice as well as resulting in various ocular surface abnormalities. Here we investigate the role of CISD2 in corneal health and disease. Methods We studied the molecular mechanism underlying the ocular phenotypes brought about by Cisd2 deficiency using both Cisd2 knockout (KO)...

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Share to Corneal surgery and disorders
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PMID: 34740104
DOI: 10.1016/j.ebiom.2021.103654

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