Article
The vaginal microbiota and innate immunity after local excisional treatment for cervical intraepithelial neoplasia.
Genome medicine - 4 Nov 2021
Mitra Anita, MacIntyre David A, Paraskevaidi Maria, Moscicki Anna-Barbara, Mahajan Vishakha, Smith Ann, Lee Yun S, Lyons Deirdre, Paraskevaidis Evangelos, Marchesi Julian R, Bennett Phillip R, Kyrgiou Maria
Abstract excerpt
BACKGROUND: Vaginal microbiota (VMB) composition is altered in women with cervical intra-epithelial neoplasia (CIN) compared to healthy controls and is associated with disease progression. However, the impact of CIN excision on the VMB and innate immunity is not known. This observational study aims to explore the impact of CIN excision on the VMB, antimicrobial peptides (AMP) and proinflammatory cytokines....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
