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Article

Changes of vaginal microbiota during cervical carcinogenesis in women with human papillomavirus infection

17 Sept 2020

Abstract excerpt

OBJECTIVE: To evaluate the changes of vaginal microbiota during cervical carcinogenesis in women with high-risk human papillomavirus infection. MATERIALS AND METHODS: Vaginal microbiota was analyzed using next-generation sequencing in women with normal, cervical intraepithelial neoplasia (CIN), or cervical cancer. RESULTS: A marked decrease of Lactobacillus crispatus was found in the CIN/cancer groups compared...

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PMID: 32941440
DOI: 10.1371/journal.pone.0238705

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