Article
Polyhydroxybutyrate-co-hydroxyvalerate structures loaded with adipose stem cells promote skin healing with reduced scarring.
Acta biomaterialia - 1 Apr 2015
Zonari Alessandra, Martins Thaís M M, Paula Ana Cláudia C, Boeloni Jankerle N, Novikoff Silviene, Marques Alexandra P, Correlo Vitor M, Reis Rui L, Goes Alfredo M
Abstract excerpt
Currently available skin substitutes are still associated with a range of problems including poor engraftment resulting from deficient vascularization, and excessive scar formation, among others. Trying to overcome these issues, this work proposes the combination of poly(3-hydroxybutyrate-co-hydroxyvalerate) (PHBV) structures with adipose-derived stem cells (ASCs) to offer biomechanical and biochemical signaling...
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