Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Effects of a Ketogenic Diet on Patients with Dihydrolipoamide Dehydrogenase Deficiency.

Nutrients - 7 Oct 2021

Staretz-Chacham Orna, Pode-Shakked Ben, Kristal Eyal, Abraham Smadar Yaala, Porper Keren, Wormser Ohad, Shelef Ilan, Anikster Yair

Abstract excerpt

BACKGROUND: Dihydrolipoamide dehydrogenase (DLD lipoamide dehydrogenase, the E3 subunit of the pyruvate dehydrogenase complex (PDHC)) is the third catalytic enzyme of the PDHC, which converts pyruvate to acetyl-CoA catalyzed with the introduction of acetyl-CoA to the tricyclic acid (TCA) cycle. In humans, PDHC plays an important role in maintaining glycose homeostasis in an aerobic, energy-generating process....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acidosis, Lactic
Share to Adolescent

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Child, Preschool

Share to Diet, Ketogenic

Share to Infant

Share to Maple Syrup Urine Disease

Share to Quality of Life

Source

Open in PubMed Open full text

Identifiers

PMID: 34684524
DOI: 10.3390/nu13103523
PMCID: PMC8540285

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Effects of a Ketogenic Diet on Patients with Dihydrolipoamide Dehydrogenase Deficiency.PMID 34684524Read ↗

Beneficial effect of pyruvate therapy on Leigh syndrome due to a novel mutation in PDH E1α gene.Semantic proximity Read ↗

The first case with FBXL4 mutation successfully treated with a parenteral ketogenic diet for lactic acidosis.Semantic proximity Read ↗

Pyruvate therapy for Leigh syndrome due to cytochrome c oxidase deficiency.Semantic proximity Read ↗

Effects of acute nutritional ketosis during exercise in adults with glycogen storage disease type IIIa are phenotype-specific: An investigator-initiated, randomized, crossover study.Semantic proximity Read ↗

Diet and Chemotherapy: The Effects of Fasting and Ketogenic Diet on Cancer TreatmentSemantic proximity Read ↗

Clinical and genetic spectrum of pyruvate dehydrogenase deficiency: dihydrolipoamide acetyltransferase (E2) deficiency.Semantic proximity Read ↗

Outcome of pyruvate dehydrogenase deficiency treated with ketogenic diets. Studies in patients with identical mutations.Semantic proximity Read ↗

Ketogenic diet in adult patients with mitochondrial myopathySemantic proximity Read ↗

The Effects of Ketogenic Diet on Seizures, Cognitive Functions, and Other Neurological Disorders in Classical Phenotype of Glucose Transporter 1 Deficiency Syndrome.Semantic proximity Read ↗

Effects of the ketogenic diet in the glucose transporter 1 deficiency syndromeSemantic proximity Read ↗

Pyruvate Improved Insulin Secretion Status in a Mitochondrial Diabetes Mellitus Patient.Semantic proximity Read ↗

Development and psychometric validation of measures to assess the impact of phenylketonuria and its dietary treatment on patients’ and parents’ quality of life: the phenylketonuria – quality of life (PKU-QOL) questionnairesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.