Article
HER2 testing by immunohistochemistry in breast cancer: A multicenter proficiency ring study.
Indian journal of pathology & microbiology - 1 Jan 2000
Md Pauzi Suria Hayati, Masir Noraidah, Yahaya Azyani, Mohammed Fazarina, Tizen Laim Nur Maya Sabrina, Mustangin Muatamarulain, Aizudin Azimatun Noor, Talib Arni, Teoh Kean-Hooi, Karim Norain, Oy-Leng Jacqueline Wong, Rajadurai Pathmanathan
Abstract excerpt
BACKGROUND: Human epidermal growth factor receptor 2 (HER2) over-expression in breast cancer is associated with aggressive tumor behavior and predicts response to targeted therapy. Accurate HER2 result is paramount for optimal patient management. However, routine HER2 immunohistochemistry (IHC) testing are subjected to intra- and inter-laboratory variability. OBJECTIVE: This study aims to determine...
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