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Article

Computational studies reveal co-occurrence of two mutations in IL7R gene of high-grade serous carcinoma patients.

Journal of biomolecular structure & dynamics - 1 Jan 2022

Wadapurkar Rucha M, Sivaram Aruna, Vyas Renu

Abstract excerpt

Major cause of mortality in ovarian cancer can be attributed to a lack of specific and sensitive biomarkers for diagnosis and prognosis of the disease. Uncovering the mutations in genes involved in crucial oncogenic pathways is a key step in discovery and development of novel biomarkers. Whole exome sequencing (WES) is a powerful method for the detection of cancer driver mutations. The present work focuses on...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34657565
DOI: 10.1080/07391102.2021.1987326

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