Article
KDR polymorphism (1192G/A, 1719A/T) and modulation of ARV drug-induced hepatotoxicity.
Microbial pathogenesis - 1 Dec 2021
Singh HariOm, Samani Dharmesh, Jadhav Sushama
Abstract excerpt
Kinase insert Domain containing Receptor (KDR)/Vascular Endothelial Growth Factor Receptor (VEGFR-2) participate in endothelial dysfunction, which can lead to chronic liver disease. KDR reflects naturally against the toxicants from the damaged liver cells. Association of KDR polymorphism has been reported with many diseases including liver disease, but its role has not been described in ARV induced...
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