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Article

MRI-based radiomics signature and clinical factor for predicting H3K27M mutation in pediatric high-grade gliomas located in the midline of the brain.

European radiology - 1 Mar 2022

Wu Chenqing, Zheng Hui, Li Jinning, Zhang Yuzhen, Duan Shaofeng, Li Yuhua, Wang Dengbin

Abstract excerpt

OBJECTIVE: To develop a nomogram based on MRI radiomics and clinical features for preoperatively predicting H3K27M mutation in pediatric high-grade gliomas (pHGGs) with a midline location of the brain. METHODS: The institutional database was reviewed to identify patients with pHGGs with a midline location of the brain who underwent tumor biopsy with preoperative MRI scans between June 2016 and June 2021. A total...

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PMID: 34655310
DOI: 10.1007/s00330-021-08234-9

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