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Article

Predicting Mutational Effects on Receptor Binding of the Spike Protein of SARS-CoV-2 Variants.

Journal of the American Chemical Society - 27 Oct 2021

Bai Chen, Wang Junlin, Chen Geng, Zhang Honghui, An Ke, Xu Peiyi, Du Yang, Ye Richard D, Saha Arjun, Zhang Aoxuan, Warshel Arieh

Abstract excerpt

The pandemic caused by SARS-CoV-2 has cost millions of lives and tremendous social/financial loss. The virus continues to evolve and mutate. In particular, the recently emerged "UK", "South Africa", and Delta variants show higher infectivity and spreading speed. Thus, the relationship between the mutations of certain amino acids and the spreading speed of the virus is a problem of great importance. In this...

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Identifiers

PMID: 34648291
DOI: 10.1021/jacs.1c07965
PMCID: PMC8525340

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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