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Transplantation of Human Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium in a Swine Model of Geographic Atrophy

28 Sept 2021

Abstract excerpt

BACKGROUND: The aim of this study was to test the feasibility and safety of subretinal transplantation of human induced pluripotent stem cell (hiPSC)-derived retinal pigment epithelium (RPE) cells into the healthy margins and within areas of degenerative retina in a swine model of geographic atrophy (GA). METHODS: = 10). Thirty days later, a suspension of hiPSC-derived RPE cells expressing green fluorescent...

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PMID: 34638840
DOI: 10.3390/ijms221910497

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