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Article

Asthma-COPD Overlap: What Are the Important Questions?

Chest - 1 Feb 2022

Leung Clarus, Sin Don D

Abstract excerpt

Asthma-COPD overlap (ACO) is a heterogeneous condition that describes patients who show persistent airflow limitation with clinical features that support both asthma and COPD. Although no single consensus definition exists to diagnose this entity, common major criteria include a strong bronchodilator reversibility or bronchial hyperreactivity, a physician diagnosis of asthma, and a ≥ 10-pack-year cigarette...

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Identifiers

PMID: 34626594
DOI: 10.1016/j.chest.2021.09.036

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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