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Article

Effects of Insomnia on Peptic Ulcer Disease Using Mendelian Randomization.

Oxidative medicine and cellular longevity - 1 Jan 2021

Zha Ling-Feng, Dong Jiang-Tao, Wang Jing-Lin, Chen Qian-Wen, Wu Jian-Fei, Zhou Ying-Chao, Nie Shao-Fang, Tu Xin

Abstract excerpt

OBJECTIVES: Observational studies indicate that insomnia may increase risk of peptic ulcer disease (PUD). Our purpose is to clarify the possible causal relationship between insomnia and PUD by Mendelian randomization analyses. METHODS: We carried out analyses using summary statistics data for genetic variants reported from a GWAS of insomnia (N = up to 1,331,010 individuals) and from a GWAS of PUD (N = up to...

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Identifiers

PMID: 34616502
DOI: 10.1155/2021/2216314
PMCID: PMC8487841

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