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Identification of disease- and headache-specific mediators and pathways in migraine using blood transcriptomic and metabolomic analysis

6 Oct 2021

Abstract excerpt

BACKGROUND: Recent data suggest that gene expression profiles of peripheral white blood cells can reflect changes in the brain. We aimed to analyze the transcriptome of peripheral blood mononuclear cells (PBMC) and changes of plasma metabolite levels of migraineurs in a self-controlled manner during and between attacks. METHODS: Twenty-four patients with migraine were recruited and blood samples were collected in...

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Share to Circadian rhythm and melatonin
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Share to Traumatic Brain Injury and Neurovascular Disturbances

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PMID: 34615455
DOI: 10.1186/s10194-021-01285-9

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