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Differential regulation of the DNA methylome in adults born during the Great Chinese Famine in 1959–1961

29 Sept 2021

Abstract excerpt

BACKGROUND: Extensive epidemiological studies have established the association between exposure to early-life adversity and health status and diseases in adults. Epigenetic regulation is considered as a key mediator for this phenomenon but analysis on humans is sparse. The Great Chinese Famine lasting from 1958 to 1961 is a natural string of disasters offering a precious opportunity for elucidating the underlying...

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PMID: 34600028
DOI: 10.1016/j.ygeno.2021.09.018

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