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Article

Crossing design shapes patterns of genetic variation in synthetic recombinant populations of Saccharomyces cerevisiae.

Scientific reports - 1 Oct 2021

Phillips Mark A, Kutch Ian C, McHugh Kaitlin M, Taggard Savannah K, Burke Molly K

Abstract excerpt

"Synthetic recombinant" populations have emerged as a useful tool for dissecting the genetics of complex traits. They can be used to derive inbred lines for fine QTL mapping, or the populations themselves can be sampled for experimental evolution. In the latter application, investigators generally value maximizing genetic variation in constructed populations. This is because in evolution experiments initiated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34599243
DOI: 10.1038/s41598-021-99026-0
PMCID: PMC8486856

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