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Article

The Correlation Between FGB Promoter Polymorphism and Clotting Function in Patients With Idiopathic Lower Extremity Deep Venous Thrombosis.

Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis - 1 Jan 2000

Han Shengbin, Yang Bin, Feng Yaoyu, Zhao Lingfeng, Feng Qun, Guan Hongxi, Song Donghui, Yin Fang, Zhuang Li

Abstract excerpt

To explore the possible single nucleotide polymorphisms (SNPs) sites in the promoter region of fibrinogen B β (FGB), and construct logistic regression model and haplotype model, so as to reveal the influence of FGB promoter SNPs on susceptibility, hemodynamics and coagulation function of lower extremity deep venous thrombosis (LEDVT) in the genetic background. LEDVT patients (120) and healthy people (120) were...

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Identifiers

PMID: 34583575
DOI: 10.1177/1076029620967108
PMCID: PMC8485564

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