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Article

Reduced ELANE and SLPI expression compromises dental pulp cell activity.

Cell proliferation - 1 Nov 2021

Sriwattanapong Kanokwan, Sa-Ard-Iam Noppadol, Boonprakong Lawan, Subbalekha Keskanya, Trachoo Vorapat, Suratannon Narissara, Porntaveetus Thantrira, Shotelersuk Vorasuk

Abstract excerpt

BACKGROUND: Patients with ELANE variants and severe congenital neutropenia (SCN) commonly develop oral complications. Whether they are caused only by low neutrophil count or the combination of neutropenia and aberrant dental cells is unknown. METHODS: Genetic variant was identified with exome sequencing. Dental pulp cells isolated from the SCN patient with an ELANE mutation were investigated for gene expression,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34580954
DOI: 10.1111/cpr.13132
PMCID: PMC8560611

Genes

ELANE
SLPI
TNF
MMP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Reduced ELANE and SLPI expression compromises dental pulp cell activity.PMID 34580954Read ↗

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