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Wnt pathway-related three-mRNA clinical outcome signature in bladder urothelial carcinoma: computational biology and experimental analyses

27 Sept 2021

Abstract excerpt

BACKGROUND: The Wnt signaling pathway is core to the growth of bladder tumors. Epithelial-to-mesenchymal transition (EMT) is significant for bladder tumor metastasis. Nevertheless, the relationship between the Wnt signaling pathway, outcomes of bladder cancer (BLCA), and the specific mechanisms driving immune infiltration have not been studied. METHODS: We obtained Wnt pathway-related gene mRNA and...

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Share to Bladder and Urothelial Cancer Treatments
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PMID: 34579753
DOI: 10.1186/s12967-021-03061-4

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