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Deletion Mutants of the Attenuated Recombinant ASF Virus, BA71ΔCD2, Show Decreased Vaccine Efficacy.

Viruses - 25 Aug 2021

Lopez Elisabeth, Bosch-Camós Laia, Ramirez-Medina Elizabeth, Vuono Elizabeth, Navas Maria Jesus, Muñoz Marta, Accensi Francesc, Zhang Jinya, Alonso Uxia, Argilaguet Jordi, Salas Maria Luisa, Anachkov Nikolay, Gladue Douglas P, Borca Manuel V, Pina-Pedrero Sonia, Rodriguez Fernando

Abstract excerpt

African swine fever (ASF) has become the major threat to the global swine industry. Lack of available commercial vaccines complicates the implementation of global control strategies. So far, only live attenuated ASF viruses (ASFV) have demonstrated solid protection efficacy at the experimental level. The implementation of molecular techniques has allowed the generation of a collection of deletion mutants lacking...

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Identifiers

PMID: 34578263
DOI: 10.3390/v13091678
PMCID: PMC8473413

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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