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Article

miR-410-3P inhibits adipocyte differentiation by targeting IRS-1 in cancer-associated cachexia patients

25 Sept 2021

Abstract excerpt

BACKGROUNDS: Cancer-associated cachexia (CAC) is a metabolic syndrome characterized by progressive depletion of adipose and muscle tissue that cannot be corrected by conventional nutritional therapy. Adipose tissue, an important form of energy storage, exhibits marked loss in the early stages of CAC, which affects quality of life and efficacy of chemotherapy. MicroRNAs (miRNAs) are a class of noncoding RNAs that...

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PMID: 34563222
DOI: 10.1186/s12944-021-01530-9

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