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Article

Herpes simplex virus and Alzheimer's disease: a Mendelian randomization study.

Neurobiology of aging - 1 Mar 2021

Kwok Man Ki, Schooling Catherine Mary

Abstract excerpt

This study assessed if any herpes simplex virus (HSV) infection was a genetically valid target for late-onset Alzheimer's disease (AD) using 2-sample Mendelian randomization. We applied strong (p-value <5×10-6) and independent (r2 < 0.05) genetic variants for any HSV infection (n = 450,581) to genome wide association studies of cognitive function (n = 300,486), and late-onset AD (n = 455,258) to obtain estimates....

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Source

Identifiers

PMID: 33139072
DOI: 10.1016/j.neurobiolaging.2020.09.025

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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