Article
RMplex: An efficient method for analyzing 30 Y-STRs with high mutation rates.
Forensic science international. Genetics - 1 Nov 2021
Ralf Arwin, Zandstra Dion, Weiler Natalie, van Ijcken Wilfred F J, Sijen Titia, Kayser Manfred
Abstract excerpt
Y-chromosomal short tandem repeats (Y-STRs) with high mutation rates are recognized as valuable genetic markers for differentiating paternally related men, who typically cannot be separated with standard Y-STRs, and were shown to provide paternal lineage differentiation on a higher resolution level than standard Y-STRs. Both features make Y-STRs with high mutation rates relevant in criminal casework, particularly...
Topics
- Chromosomes, Human, Y
- DNA Fingerprinting
- Female
- Genotype
- Haplotypes
- Humans
- Male
- Microsatellite Repeats
- Mutation
- Mutation Rate