Relationship between functional Nrf2 gene promoter polymorphism and sperm DNA damage in male infertility.

doi:10.1080/19396368.2021.1972359

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Relationship between functional Nrf2 gene promoter polymorphism and sperm DNA damage in male infertility.

Systems biology in reproductive medicine - 1 Dec 2021

Aydos O Sena, Yukselten Yunus, Aydos Dunya, Sunguroglu Asuman, Aydos Kaan

Abstract excerpt

This study examines the association of the -617 C > A polymorphism in the Nrf2 gene (rs6721961) with male infertility in a Turkish population and determines its functional role in spermatogenesis in correlation with the impact of different levels of DNA damage on the genotypes. A total of 100 infertile men and 100 healthy fertile men were included in the study. Nrf2 genotyping was performed with the PCR-based...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arylamine N-Acetyltransferase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Damage

Share to Genomics, phytochemicals, and oxidative stress

Share to Genotype

Share to Infertility, Male

Share to NF-E2-Related Factor 2

Share to Polymorphism, Genetic

Share to Spermatozoa

Source

Open in PubMed

Identifiers

PMID: 34541983
DOI: 10.1080/19396368.2021.1972359

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Relationship between functional Nrf2 gene promoter polymorphism and sperm DNA damage in male infertility.PMID 34541983Read ↗

Genetic variation in the Nrf2 promoter associates with defective spermatogenesis in humans.Semantic proximity Read ↗

Cigarette smoking is associated with human semen quality in synergy with functional NRF2 polymorphisms.Semantic proximity Read ↗

Low NRF2 mRNA Expression in Spermatozoa from Men with Low Sperm MotilitySemantic proximity Read ↗

Variations in Antioxidant Genes and Male InfertilitySemantic proximity Read ↗

Oxidative Stress Biomarkers in Male Infertility: Established Methodologies and Future PerspectivesSemantic proximity Read ↗

Role of nuclear factor erythroid 2-related factor 2 (Nrf2) in female and male fertilitySemantic proximity Read ↗

Glutathione S-transferase genetic polymorphisms and fluoride-induced reproductive toxicity in men with idiopathic infertility.Semantic proximity Read ↗

Impact of oxidative stress SNPs on sperm DNA damage and male infertility in a south-east Iranian population.Semantic proximity Read ↗

The Incriminating Role of Reactive Oxygen Species in Idiopathic Male Infertility: An Evidence Based EvaluationSemantic proximity Read ↗

Unravelling the epigenetic impact: Oxidative stress and its role in male infertility-associated sperm dysfunctionSemantic proximity Read ↗

Is male infertility associated with increased oxidative stress in seminal plasma? A-meta analysisSemantic proximity Read ↗

Metabolic enzyme gene polymorphisms predict the effects of antioxidant treatment on idiopathic male infertility.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.