Article
RIC3 variants are not associated with Parkinson's disease in large European, Latin American, or East Asian cohorts.
Neurobiology of aging - 1 Jan 2022
Brolin Kajsa, Bandres-Ciga Sara, Leonard Hampton, Makarious Mary B, Blauwendraat Cornelis, Mata Ignacio F, Foo Jia Nee, Pihlstrøm Lasse, Swanberg Maria, Gan-Or Ziv, Tan Manuela Mx
Abstract excerpt
Parkinson's disease (PD) is a complex neurodegenerative disorder in which both rare and common genetic variants contribute to disease risk. Multiple genes have been reported to be linked to monogenic PD but these only explain a fraction of the observed familial aggregation. Rare variants in RIC3 have been suggested to be associated with PD in the Indian population. However, replication studies yielded...
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